Tuning cellular responses to BMP-2 with material surfaces
نویسندگان
چکیده
منابع مشابه
Gremlin1 preferentially binds to bone morphogenetic protein-2 (BMP-2) and BMP-4 over BMP-7.
Gremlin (Grem1) is a member of the DAN family of secreted bone morphogenetic protein (BMP) antagonists. Bone morphogenetic protein-7 (BMP-7) mediates protective effects during renal fibrosis associated with diabetes and other renal diseases. The pathogenic mechanism of Grem1 during diabetic nephropathy (DN) has been suggested to be binding and inhibition of BMP-7. However, the precise interacti...
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ژورنال
عنوان ژورنال: Cytokine & Growth Factor Reviews
سال: 2016
ISSN: 1359-6101
DOI: 10.1016/j.cytogfr.2015.11.008